Publications
Designing protein nanopores for capturing and degrading microplastics
Manuel Ferrer, Ana Robles-Martín, Sara García-Linares, Álvaro Martínez-del-Pozo, and Víctor Guallar.
Fantastic enzymes: where and how to find them.
Patricia Molina Espeja, Markus Müller, Sara Daniotti, Manuel Ferrer, & the FuturEnzyme Consortium.
Searching for enzymes: reason, the environment.
12 October 2021 21:47 CEST (Text of the link in Spanish).
The use of enzymes to achieve more sustainable everyday consumer products.
Manuel Ferrer, Patricia Molina, Carolina Peñalva. Ambienta Journal Nº 128, 2021 second quarter. Innovation section. ISSN: 1577-9491.(Text of the link in Spanish).
Scientific publications
Unlocking a Key Residue in a Lipase for Efficient Polyethylene Terephthalate (PET) Hydrolysis and Influencing Depolymerization Product Profiles.
Paula Vidal, Ana Robles-Martín, Laura Fernandez-Lopez, Jose L. Gonzalez-Alfonso, David Almendral, Ruben Muñoz-Tafalla, Francisco J. Plou, Víctor Guallar and Manuel Ferrer.
Microbial communities colonising plastics during transition from the wastewater treatment plant to marine waters.
Constance L. Tulloch, Rafael Bargiela, Gwion B. Williams, Tatyana N. Chernikova, Benjamin M. Cotterell, Elizabeth M. H. Wellington, Joseph Christie‑Oleza, David N. Thomas, Davey L. Jones and Peter N. Golyshin.
Moderately thermostable GH1 β-glucosidases from hyperacidophilic archaeon Cuniculiplasma divulgatum S5.
Anna N Khusnutdinova, Hai Tran, Saloni Devlekar, Marco A Distaso, Ilya Kublanov, Tatiana Skarina, Peter Stogios, Alexei Savchenko, Manuel Ferrer, Olga Golyshina, Alexander F Yakunin, Peter Golyshin.
Interplay of intracellular and trans-cellular DNA methylation in natural archaeal consortia.
Oleg N Reva, Violetta La Cono, Francesca Crisafi, Francesco Smedile, Manasi Mudaliyar, Debnath Ghosal, Laura Giuliano, Mart Krupovic, Michail M Yakimov.
Exploiting cyclodextrins as artificial chaperones to enhance enzyme protection through supramolecular engineering.
Ali Foroutan Kalourazi, Seyed Amirabbas Nazemi, Ajmal Roshan Unniram Parambil, Ruben Muñoz-Tafalla, Paula Vidal, S. Shirin Shahangian, Victor Guallar, Manuel Ferrer, Patrick Shahgaldian.
Behind the Scenes of PluriZyme Designs.
Ana Robles-Martín, Sergi Roda, Rubén Muñoz-Tafalla, Víctor Guallar.
Halopseudomonas species: Cultivation and molecular genetic tools.
Luzie Kruse, Anita Loeschcke, Jan de Witt, Nick Wierckx, Karl-Erich Jaeger, Stephan Thies.
Isolation and Characterization of a Serratia rubidaea from a Shallow Water Hydrothermal Vent.
Ricardo F.S. Pereira, Maria J.Ferreira, M. Conceição Oliveira, Maria C. Serra, Carla C. C. R. de Carvalho.
Sub-micro- and nano-sized polyethylene terephthalate deconstruction with engineered protein nanopores.
Ana Robles-Martín, Ana, Rafael Amigot-Sánchez, Laura Fernandez-Lopez, Jose L. Sergi Roda, Víctor Alcolea-Rodriguez, Diego Heras-Márquez, David Almendral, Cristina Coscolín, Francisco J. Plou, Raquel Portela, Miguel A. Bañares, Álvaro Martínez-del-Pozo, Sara García-Linares, Manuel Ferrer, Víctor Guallar.
An archaeal lid-containing feruloyl esterase degrades polyethylene terephthalate.
Pablo Perez-Garcia, Jennifer Chow, Elisa Costanzi, Marno Gurschke, Jonas Dittrich, Robert F. Dierkes, Rebecka Molitor, Violetta Applegate, Golo Feuerriegel, Price Tete, Dominik Danso, Stephan Thies, Julia Schumacher, Christopher Pfleger, Karl-Erich Jaeger, Holger Gohlke, Sanders Smits, Ruth A. Schmitz, Wolfgang R. Streit.
Nanobiocatalysts with inbuilt cofactor recycling for oxidoreductase catalysis in organic solvents.
Jenny Sahlin, Congyu Wu, Andrea Buscemi, Claude Schärer, Seyed Amirabbas Nazemi, Rejaul S. K., Nataly Herrera-Reinoza, Thomas A. Jung, Patrick Shahgaldian.
Functional diversity of nanohaloarchaea within xylan-degrading consortia.
Oleg Reva, Enzo Messina, Violetta La Cono, Francesca Crisafi, Francesco Smedile, Gina La Spada, Laura Marturano, Elena A. Selivanova, Manfred Rohde, Mart Krupovic, M. Yakimov Michail.
A Choice Experiment Model for Sustainable Consumer Goods: A Systematic Literature Review and Workflow Design.
Maria Elena Saija, Sara Daniotti, Diego Bosco, Ilaria Re.
Enhancing the Hydrolytic Activity of a Lipase towards Larger Triglycerides through Lid Domain Engineering.
Laura Fernandez-Lopez, Sergi Roda, Ana Robles-Martín, Rubén Muñoz-Tafalla, David Almendral, Manuel Ferrer, Víctor Guallar.
The metagenome-derived esterase PET40 is highly promiscuous and hydrolyses polyethylene terephthalate (PET).
Hongli Zhang, Robert F. Dierkes, Pablo Perez-Garcia, Elisa Costanzi, Jonas Dittrich, Pablo A. Cea, Marno Gurschke, Violetta Applegate, Kristina Partus, Christel Schmeisser, Christopher Pfleger, Holger Gohlke, Sander H. J. Smits, Jennifer Chow, Wolfgang R. Streit.
Harnessing extremophilic carboxylesterases for applications in polyester depolymerisation and plastic waste recycling.
Gwion B. Williams, Hairong Ma, Anna N. Khusnutdinova, Alexander F. Yakunin, Peter N. Golyshin.
Transforming an esterase into an enantioselective catecholase through bioconjugation of a versatile metal-chelating inhibitor.
Laura Fernandez-Lopez, Isabel Cea-Rama, Julia Alvarez-Malmagro, Anna K. Ressmann, Jose L. Gonzalez-Alfonso, Cristina Coscolín, Patrick Shahgaldian, Francisco J. Plou, Jan Modregger, Marcos Pita, Julia Sanz-Aparicio, Manuel Ferrer.
Nanohaloarchaea as beneficiaries of xylan degradation by haloarchaea.
Violetta La Cono, Enzo Messina, Oleg Reva, Francesco Smedile, Gina La Spada, Francesca Crisafi, Laura Marturano, Noa Miguez, Manuel Ferrer, Elena A. Selivanova, Olga V. Golyshina, Peter N. Golyshin, Manfred Rohde, Mart Krupovic, Alexander Y. Merkel, Dimitry Y. Sorokin, John E. Hallsworth, Michail M. Yakimov.
Increased Thermostability of an Engineered Flavin-Containing Monooxygenase to Remediate Trimethylamine in Fish Protein Hydrolysates.
Marianne Goris, Isabel Cea-Rama, Pål Puntervoll, David Almendral, Julia Sanz-Aparicio, Manuel Ferrer, Gro Elin Kjæreng Bjerga.
AsiteDesign: a Semirational Algorithm for an Automated Enzyme Design.
Sergi Roda, Henrik Terholsen, Jule Ruth Heike Meyer, Albert Cañellas-Solé, Víctor Guallar, Uwe Bornscheuer, Masoud Kazemi.
Enzymes for consumer products to achieve climate neutrality.
Patricia Molina-Espeja, Julia Sanz-Aparicio, Peter N Golyshin, Ana Robles-Martín, Víctor Guallar, Fabrizio Beltrametti, Markus Müller, Mikhail Yakimov, Jan Modregger, Moniec van Logchem, Philippe Corvini, Patrick Shahgaldian, Christian Degering, Susanne Wieland, Anne Timm, Carla C C R de Carvalho, Ilaria Re, Sara Daniotti, Stephan Thies, Karl-Erich Jaeger, Jennifer Chow, Wolfgang R Streit, Roland Lottenbach, Rainer Rösch, Nazanin Ansari & Manuel Ferrer, The FuturEnzyme Consortium.
Enzyme adaptation to habitat thermal legacy shapes the thermal plasticity of marine microbiomes.
Ramona Marasco, Marco Fusi, Cristina Coscolín, Alan Barozzi, David Almendral, Rafael Bargiela, Christina Gohlke neé Nutschel, Christopher Pfleger, Jonas Dittrich, Holger Gohlke, Ruth Matesanz, Sergio Sanchez-Carrillo, Francesca Mapelli, Tatyana N. Chernikova, Peter N. Golyshin, Manuel Ferrer and Daniele Daffonchio.
Metagenomics and new enzymes for the bioeconomy to 2030 (In: Biotechnology of Microbial Enzymes).
Patricia Molina-Espeja, Cristina Coscolín, Peter N. Golyshin, Manuel Ferrer.
Assigning Functions of Unknown Enzymes by High-Throughput Enzyme Characterization.
Patricia Molina-Espeja, Laura Fernandez-Lopez, Peter N. Golyshin & Manuel Ferrer.
Thermophilic Carboxylesterases from Hydrothermal Vents of the Volcanic Island of Ischia Active on Synthetic and Biobased Polymers and Mycotoxins.
Marco A. Distaso, Tatyana N. Chernikova, Rafael Bargiela, Cristina Coscolín, Peter Stogios, Jose L. Gonzalez-Alfonso, Sofia Lemak, Anna N. Khusnutdinova, Francisco J. Plou, Elena Evdokimova, Alexei Savchenko, Evgenii A. Lunev, Michail M. Yakimov, Olga V. Golyshina, Manuel Ferrer, Alexander F. Yakunin, Peter N. Golyshin.
The Mobility of the Cap Domain Is Essential for the Substrate Promiscuity of a Family IV Esterase from Sorghum Rhizosphere Microbiome.
Marco Distaso, Isabel Cea-Rama, Cristina Coscolín, Tatyana N. Chernikova, Hai Tran, Manuel Ferrer, Julia Sanz-Aparicio, Peter N. Golyshin .
Design and Characterization of In-One Protease-Esterase PluriZyme.
Laura Fernandez-Lopez, Sergi Roda, Jose L. Gonzalez-Alfonso, Francisco J. Plou, Víctor Guallar, Manuel Ferrer.
Marine Bioprospecting, Biocatalysis and Process Development.
Carlos J. C. Rodrigues, Carla C. C. R. de Carvalho.
EP-Pred: A Machine Learning Tool for Bioprospecting Promiscuous Ester Hydrolases.
Ruite Xiang, Laura Fernandez-Lopez, Ana Robles-Martín, Manuel Ferrer and Victor Guallar.
A novel metagenome‑derived viral RNA polymerase and its application in a cell‑free expression system for metagenome screening.
Yuchen Han, Birhanu M. Kinfu, Fabian Blombach, Gwenny Cackett, Hongli Zhang, Pablo Pérez‑García, Ines Krohn, Jesper Salomon, Volkan Besirlioglu, Tayebeh Mirzaeigarakani, Ulrich Schwaneberg, Jennifer Chow, Finn Werner, Wolfgang R. Streit.
Plasmonic photothermal activation of an organosilica shielded cold-adapted lipase co-immobilised with gold nanoparticles on silica particles.
Carolina I. Giunta, Seyed Amirabbas Nazemi, Magdalena Olesińska, Patrick Shahgaldian.
Cultivating marine bacteria under laboratory conditions: Overcoming the “unculturable” dogma.
Carlos J. C. Rodrigues, Carla C. C. R. de Carvalho.
A plurizyme with transaminase and hydrolase activity catalyzes cascade reactions.
Sergi Roda, Laura Fernandez-Lopez, Marius Benedens, Alexander Bollinger, Stephan Thies, Julia Schumacher, Cristina Coscolín, Masoud Kazemi, Gerard Santiago, Christoph G. W. Gertzen, Jose L. Gonzalez-Alfonso, Francisco J. Plou, Karl-Erich Jaeger, Sander H. J. Smits, Manuel Ferrer, Víctor Guallar.
Crystal structure of a family VIII β-lactamase fold hydrolase reveals the molecular mechanism for its broad substrate scope.
Isabel Cea-Rama, Cristina Coscolín, José Luis Gonzalez-Alfonso, Jog Raj, Marko Vasiljević, Francisco J Plou, Manuel Ferrer, Julia Sanz-Aparicio.
Metagenomic Mining for Esterases in the Microbial Community of Los Rueldos Acid Mine Drainage Formation.
Paula Vidal, Mónica Martínez-Martínez, Laura Fernandez-Lopez, Sergi Roda, Celia Méndez-García, Olga V Golyshina, Víctor Guallar, Ana I Peláez, Manuel Ferrer.
Process Development for Benzyl Alcohol Production by Whole-Cell Biocatalysis in Stirred and Packed Bed Reactors.
Carlos J. C. Rodrigues, Carla C. C. R. de Carvalho.
Calm and Frenzy: marine obligate hydrocarbonoclastic bacteria sustain ocean wellness.
Michail M. Yakimov, Rafael Bargiela, Peter N. Golyshin.
Halapricum desulfuricans sp. nov., carbohydrate-utilizing, sulfur-respiring haloarchaea from hypersaline lakes.
Dimitry Y. Sorokina, Michail M. Yakimov, Enzo Messina, Alexander Y. Merkel, Michel Koenen, Nicole J. Bale, Jaap S. Sinninghe Damsté.
Cultivation of a vampire: 'Candidatus Absconditicoccus praedator'.
Michail M. Yakimov, Alexander Y. Merkel, Vasil A. Gaisin, Martin Pilhofer, Enzo Messina, John E. Hallsworth, Alexandra A. Klyukina, Ekaterina N. Tikhonova, Vladimir M. Gorlenko.
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